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College of Science and Mathematics > Department of Biochemistry, Chemistry, and Physics > Faculty and Staff > Dr. Will E. Lynch

Dr. Will E. Lynch


Chair, Department of Biochemistry, Chemistry and Physics            Professor of Chemistry
Specialization:  Inorganic Chemistry

Education

  • B. A. Kalamazoo College – Chemistry (ACS Certified) & Mathematics (1986)
  • Ph.D. Wayne State University – Inorganic Chemistry (1991)
  • Postdoctoral Fellow  University of Georgia (1991-1993)

Dr. Lynch received his B.A. degrees in chemistry and mathematics from Kalamazoo College in 1986.  During his time in Kalamazoo he interned for 2 years with the Kalamazoo Spice and Extract Company (Kalsec) under the direction of Dr. Richard Cook and did his Senior Independent Project with Dr. Thomas Smith on the synthesis and characterization of quadruple bonded molybdenum complexes.  His Ph.D. was awarded in 1991 under the direction of Dr. Richard Lintvedt at Wayne State University where he studied oxygen atom transfer reactions in osmium complexes.  Dr. Lynch completed a postdoctoral fellowship at the University of Georgia under the direction of Dr. Donald Kurtz.  His work focused on activation of molecular oxygen using copper complexes.   Dr. Lynch joined the chemistry program at Armstrong State College in 1993 which post-consolidation is now Georgia Southern University.

Dr. Lynch’s research interests include synthetic inorganic chemistry and the use of metal complexes for catalysis and modeling biological systems.  This includes coordination chemistry, coordination polymers and  halogen bonding interactions.

Research

  1.  Coordination Polymers – We have an interest in new materials, specifically using metals and molecules with variable coordination modes that allow us to construct novel polymeric materials.  In our hands, the N-oxide motif provides a very flexible/versatile ligand system that allows for the construction of unique materials.
  2. Synthetic Modeling of Bioinorganic Systems – We have used tri- and bidentate ligand systems to synthesize novel structural and functional models of protein sites found in nature.  This example is of a novel copper active site of quercetin dioxygenase.
  3. Halogen Bonding – There is an increase in interest in examining the properties of halogen bonding species. The interactions have become much more prevalent in recent electronic applications as well as being noted in biological systems.
  4. Novel Transition Metal Complexes – We have synthesized a number of new transition metal complexes.  These studies are driven by our interest in finding new complexes as possible catalytic agents.

Teaching – Courses Taught

  • CHEM 1151 / 1152 – Survey of Chemistry I and II
  • CHEM 1211 / 1212 – Principles of Chemistry I and II
  • CHEM 2100 – Analytical Chemistry
  • CHEM 3300 – Inorganic Chemistry
  • Advanced Topics Courses – Organometallics, Group Theory, Bioinorganic Chemistry, Inorganic NMR, X-ray Crystallography & Green Chemistry

Recent Publications (2015-present)

  1. Padgett, C.W.; Dean, R.; Cobb, A.; Miller, A.; Gotz, A.; Bailey, S.; Hillis, K.; McMillen, C.; Toney, S.; Guillet, G.; Lynch, W.; Pennington, W. “Comparison of N..I and N..O halogen bonds in organoiodine cocrystals of heterocyclic aromatic diazine mono N-oxides” Cryst. Growth & Design 2023, under review.
  2. Padgett, C.W.; Lynch, W.E.; Groneck, E.N.; Raymundo, M.; Adams, D. “Crystal Structures of three zinc(II) halide coordination complexes with quinolone N-oxide” Acta. Cryst. Sect. E, 2022, 78(7), 716-721.
  3. Traver, J.; Chenard, E. Zeller, M.; Guillet, G.L.; Lynch, W.E.; Hillesheim, P.C. “Directing cation-cation interactions in thiamine compounds: Analysis of a series of organic salts based on vitamin B1” J. Mol. Struct. 2021, 1232, 130046.
  4. 4. Beasley, E.M.; Bazemore, J.G.; Petrillo, A.; Padgett, C.W.; Lynch, W. E.; Quillian, B.
    “Preparation of 3-hydroxy-2,3-dialkoxy-2-phenylchroman-4-ones and 3,3-dihydroxy-2-alkoxy-2-phenylchroman-4-ones by oxidation of 3-hydroxyflavone with copper(II) bromide: Structure, reactivity and characterization” Inorganica Chimica Acta, 2020, 512 1, 119855
  5. Padgett, C.W.; Sheriff, K.; Lynch, W.E. “Pyridine-4-carboxamidoxime N-oxide” IUCrData, 2020, 5, x201335.
  6. Lynch, W.E.; Whitlock, C.R.; Padgett, C.W. “Ethyl 1H-indole-2-carboxylate” IUCrData, 2020, 5, x201205.
  7. Lynch, W.E.; Nivens, D. Quillian, B.P.; Padgett, C.W.; Petrillo, A.; Peek, N.; Stone, J. “A Copper(II) tris-imidazolylphosphine complex as a functional model of flavonol 2,4-dioxygenase”
    J. Mol. Struct. 2019, 1185, 99-106.
  8. Lynch, S.; Lynch, G.; Lynch, W.E.; Padgett, C.W. “Crystal structures of four dimeric manganese(II) bromide coordination complexes with various derivatives of pyridine N- oxide” Acta Cryst. E Res. Comm. 2019, E75, 1284-1290.
  9. Quillian, B.P.; Lynch, W.E.; Padgett, C.W.; Lorbecki, A.; Petrillo, A.; Tran, M. “Syntheses and Crystal Structures of Copper(II) Bis(pyrazolyl)acetic Acid Complexes” J. Chem. Cryst. 2018, 49(1), 1-7.
  10. Lynch, W.E.; Lynch, G.; Sheriff, K.; Padgett, C.W. “Structures of substituted pyridine N-oxide with manganese(II) acetate.” Acta Cryst. 2018, E74, 1405-1410.
  11. Padgett, C.W.; Lynch, W.E.; Sheriff, K.; Dean, R.; Zingales, S. “2,2’-Disulfanediylbis(pyridine
    N- oxide)-hydrogen peroxide (1/1).” International Union of Crystallography Data, 2018, 3, x180320.
    12. Lynch, W.E.; Padgett, C.W. “3-Hydroxy-2-(4-methylphenyl)-4H-chromen-4-one” International Union of Crystallography Data, 2018, 3, x181138.
  12. Lynch, W.E.; Padgett, C.W., Schafer, S. “2-Chloro-4-nitropyridine N-oxide.” International Union of Crystallography Data, 2018, 3, x180016.
  13. Kang, L.; Lynch, G.; Lynch, W.E.; Padgett, C.W. “Manganese(II) chloride complexes with pyridine N-oxide (PNO) derivatives and their solid state structures.” Acta Cryst. 2017, E73, 1434-1438,
  14. Lynch, W.E.; Padgett, C.W. “Bis(flavonolate-k2O,O’)dioxoosmium(VI) dichloromethane disolvate” International Union of Crystallography Data, 2017,  2, x171391.
  15. Carter, J.; Weaver, B.; Chiacchio, M.A.; Messersmith, A.R.; Lynch, W.E.; Feske, B.D.; Gumina, G “Synthesis, stereochemical characterization, and antimicrobial evaluation of a potential non-nephrotoxic 3’-C-acethydrazide puromycin analog” Journal of Nucleosides, Nucleotides and Nucleic Acids, 2017, 36 (3), 224-241.
  16. Raymundo, M.; Padgett, C.W.; Lynch, W.E. “Tris(2-methoxyphenyl)phosphine selenide” International Union of Crystallography Data, 2017, 2, x170009.
  17. Raymundo, M.; Padgett, C.W.; Lynch, W.E. “Tris(4-methoxyphenyl)phosphine selenide” International Union of Crystallography Data, 2016, 1, x161271.
  18. Lynch, W. E.; Padgett, C.W.; Quillian, B.; Haddock, J. “A square-planar hydrated cationic tetrakis(methimazole)gold(III) complex.” Acta Cryst. C 2015, C71, 298-300.
  19. Hutchinson, M.G.; Lynch, W.E.; Padgett, C.W. “Crystal structure of 3-bromopyridne N-oxide” Acta Cryst. E 2015, E71, o869.
  20. Prichard, A.M.; Lynch, W. E.; Padgett, C.W. “Crystal structure of 2,6-dichloro-4-nitropyridine N-oxide” Acta Cryst. E. 2015, E71, o775.

Last updated: 1/29/2024

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